Associate Scientist in HPLC Purification
Job description
Spectrix Analytical Services, LLC is seeking a highly motivated BS- or MS-level chemist with small molecule analytical and purification skills to work in our laboratories to advance drug discovery programs toward the clinic. In this laboratory-based position, the successful candidate will perform high throughput purification of small molecule pharmaceuticals from medicinal chemists. This includes the purification of compounds from focused chemical libraries or singleton samples with mass-directed reversed-phase High Performance Liquid Chromatography (RP-HPLC). She/he will maintain close interactions with scientists from Discovery Chemistry, Discovery Process Chemistry and Parallel Medicinal Chemistry teams to expedite the compound design-synthesis-test iterations. Strong people skills and the ability to thrive in a team and goal driven environment are key attributes.
Responsibilities:
- Conduct daily system suitability check on LCMS instrumentation
- Maintain instrument in good working condition and perform troubleshooting analysis and maintenance as required
- Assist with preliminary screening experiments prior to sample purification and post purification sample downstream handling
- Conduct large scale (grams) purification work for small molecules
- Support lab operations and maintain general lab orderliness
- Assist in the maintenance of a safe working environment and operate in a safe manner
- Other duties and assignments as needed to support the lab operations
Qualifications
- A minimum of a bachelor’s degree in Analytical, Synthetic, Organic, Medicinal Chemistry or related chemistry degree is required
- Minimum of 2 years purification and mass spectrometry experience required
- Knowledge of modern analytical techniques, such as analytical HPLC and mass spectrometry
- Independent thinking and the ability to effectively collaborate in a highly matrixed environment
- Detail oriented with strong organization and communication skills
- Experience with Waters equipment with Masslynx software preferred
Spectrix offers flexible schedules, competitive salaries, and a committed work environment to its employees; the company provides automatic benefits of life insurance and short and long term disability insurance. Optional benefits for full time employees include health, dental, and vision insurance, college loan assistance, and an employer matched retirement savings plan. Spectrix is not a placement agency. Spectrix is participating in the E-Verify program of the U.S. Department of Homeland Security (phone number: 888-897-7781, and website: www.dhs.gov/E-Verify).
Job Type: Full-time
Pay: $25.00 - $40.00 per hour
Benefits:
- 401(k)
- 401(k) matching
- Dental insurance
- Flexible schedule
- Flexible spending account
- Health insurance
- Health savings account
- Life insurance
- Paid time off
- Referral program
- Retirement plan
- Tuition reimbursement
- Vision insurance
Schedule:
- 8 hour shift
- Monday to Friday
COVID-19 considerations:
Client vaccination policy requires all staff to be fully vaccinated against Covid-19 to work on-site.
Experience:
- LC/MS: 1 year (Required)
- Industry: 1 year (Required)
Work Location: One location
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