Director of Clinical Pharmacology in Neuroscience & Vaccines and Immune Therapies

Cambridge UK, Gaithersburg MD, US

Salary & Benefits Competitive

Make a more meaningful impact to patients’ lives around the globe

With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much, yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.

Be encouraged and supported to think creatively in our dynamic environment. Here we are free from fear of failure, free to ask the right questions and make bold decisions.

Within the Clinical Pharmacology and Safety Sciences function, we have a state-of-the-art quantitative clinical pharmacology group with a diverse and uniquely skilled team of clinical pharmacometricians and clinical pharmacology scientists. Cambridge and Gaithersburg are key research and development locations for our Vaccines and Immune Therapies & Neuroscience area.

What you will do:

You will work closely with clinical pharmacometricians, physicians and other scientists, and apply your expertise and leadership skills to contribute to the strategy of the clinical program and the design and interpretation of clinical studies. You will influence key decisions in early and late phases of clinical development. Accountable for expert data integration, analysis, interpretation, and reporting of clinical pharmacology results at the study level in compliance with Good Clinical Practice (GCP) regulations and internal/external mentorship, in support of projects (project team/governance). Jointly accountable with the clinical pharmacometrician for providing a scientific justification for the dose selection, for representing Clinical Pharmacology and Quantitative Pharmacology in cross-functional project teams, and for developing the clinical pharmacology strategy. Participation in and accountability for peer review of ongoing activities, reports and presentations. Contribute to regulatory documents and interactions (written and oral). Presentation of Clinical Pharmacology results within and outside of AstraZeneca and publish in peer reviewed journals. Contribute to internal initiatives to develop the clinical pharmacology field including its processes.

Essential Criteria

• PhD or equivalent (e.g. Pharm.D/M.Sc. with postdoctoral research training) degree in a relevant field
• Industry experience or equivalent in pharmacokinetics and clinical pharmacology aspects of early and late phase drug development
• Experience of writing and reviewing clinical trial protocols and reports and regulatory documents such as INDs, IBs, NDAs or BLAs
• Knowledge in pharmacokinetics, pharmacology, drug targets, its clinical application and regulatory context and core disease areas
• Good oral and written communication skills

Desirable Criteria

• Translational science experience
• International scientific reputation gained from scientific publishing in the field of Clinical Pharmacology

Why AstraZeneca

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.

So, what’s next?

Complete your application before the below closing date.

This role is open from 30/08/2022, we welcome with your application no later than 27/09/2022

Where can I find out more?

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