Job description

Job Description:

We are seeking a highly motivated BS- or MS-level chemists with analytical and purification skills to work in our laboratories to advance small molecule drug discovery programs toward the clinic. In this laboratory-based position, the successful candidate will assist the high throughput purification services to medicinal chemists. This includes purifying compounds from focused chemical libraries or singleton samples with mass-directed reverse phase HPLC. She/he will maintain close interactions with scientists from discovery chemistry, discovery process chemistry and parallel medicinal chemistry to expedite the compound design-synthesis-test iterations. Strong people skills and the ability to thrive in a team and goal driven environment are key attributes.

Responsibilities

• Conduct daily system suitability check on Analytical LC/MS and Tecan Liquid Handler. Maintain instrument in good working condition.
• Assist in running the preliminary screening experiments prior to sample purification and post purification sample downstream handling.
• Conduct large scale (grams) and micro scale (sub-mg) purification work for small molecules.
• Support lab operation. To include, but not limited to prepare reference standard, refill media/buffers for laboratory experiments when it’s needed and switch waste bin/waste solvent bottles when full.
• Collect, place and monitor lab reagent orders.
• Support all shipping and receiving samples.
• Maintain general lab orderliness. Regular equipment maintenance, water bath and equipment/work space cleaning.
• Assist in the maintenance of a safe working environment and operate in a safe manner.
• Other duties and assignments as needed to support the lab operations.

Qualifications

• A minimum of a bachelor’s degree in Analytical, Synthetic, Organic, Medicinal chemistry or related chemistry degree is required.
• Knowledge of modern analytical techniques, such as analytical HPLC and MS detector experience preferred.
• Independent thinking and the ability to effectively collaborate in a highly matrixed environment.
• Must be detail oriented with strong organization/communication skills and have good documentation practices.

Job Type: Full-time

Job Types: Full-time, Contract

Pay: $25.00 - $40.00 per hour

Benefits:

• 401(k)
• 401(k) matching
• Dental insurance
• Employee assistance program
• Flexible schedule
• Flexible spending account
• Health insurance
• Health savings account
• Life insurance
• Paid time off
• Parental leave
• Professional development assistance
• Referral program
• Retirement plan
• Tuition reimbursement
• Vision insurance

Schedule:

• 8 hour shift

COVID-19 considerations:
Vaccination required

Ability to commute/relocate:

• Spring House, PA: Reliably commute or planning to relocate before starting work (Required)

Education:

• Bachelor's (Required)

Experience:

• Laboratory experience: 2 years (Required)
• HPLC: 2 years (Required)

Work Location: In person

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