Research Associate, Next Generation Therapeutics, New Venture Labs
Full Time
Cambridge, MA 02139
Posted
Job description
The Role:We are seeking a highly motivated individual to execute early discovery of novel antibodies and protein engineering of biotherapeutics for encoding into Moderna’s mRNA technology platform. The ideal candidate will have demonstrated capacity to function in a fast-paced laboratory environment with cross-functional teams.
Here’s What You’ll Do:
Execute experiments in the lab to discover and characterize novel antibodies in support of programs in the Next Generation Biotherapeutics Group.
Culture mammalian cells and select cells using FACS-Sorting techniques.
Work with automated assay systems.
Execute basic molecular biology, cell transfections, PCR and understand expression vector design.
Capable of computer driven sequence alignments and primer design.
Perform in vitro assays to characterize cell lines and engineered proteins for example: ELISAs, FACS, Western blotting, and cell proliferation assays.
Express, purify and characterize proteins using mammalian expression systems.
Determine protein binding affinities using techniques such as FACS, OCTET and Biacore.
Learn to use formulated mRNA to express molecules in vivo and in vitro.
Write protocols, maintain notebook with detailed account of experiments
General laboratory responsibilities including lab equipment maintenance, preparation of reagents, and the ordering and receiving of lab supplies.
Closely collaborate research group members both within and outside the company in support of therapeutic programs
Here’s What You’ll Bring to the Table:
BS/BA in biology, biochemistry, or other related discipline
Lab experience with mammalian cell culture (cell lines and primary cells).
Hands on experience with cell-based assays.
Laboratory experience in basic molecular biology skills.
Capable of designing and execute a variety of protein characterization assays.
Ability to write protocols and analyze data.
Strong communication skills and interest in doing lab work, and the ability to work independently in a dynamic environment.
Experience with operation of FACS and/or FACS cell sorting.
Ability to execute general molecular biology techniques, PCR, primer design, transiently transfect and express proteins in 293 cells.
Able to design and execute protein characterization experiments.
Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:
Highly competitive and inclusive medical, dental and vision coverage options
Flexible Spending Accounts for medical expenses and dependent care expenses
Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
Family care benefits, including subsidized back-up care options and on-demand tutoring
Free premium access to fitness, nutrition, and mindfulness classes
Exclusive preferred pricing on Peloton fitness equipment
Adoption and family-planning benefits
Dedicated care coordination support for our LGBTQ+ community
Generous paid time off, including:
- Vacation, sick time and holidays
- Volunteer time to participate within your community
- Discretionary winter shut down
- Paid sabbatical after 5 years; every 3 years thereafter
401k match and Financial Planning tools
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Complimentary concierge service including home services research, travel booking, and entertainment requests
Free parking or subsidized commuter passes
Location-specific perks and extras!
Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible . Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.
About Moderna
In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.
Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com .
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. #LI-AM1
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