Scientist I (Innovation Department)

Full Time
Houston, TX 77054
Posted
Job description

NuProbe is the US-based R&D subsidiary of NuProbe Global, a company devoted to the development of novel non-invasive DNA and RNA diagnostic assays. Currently, NuProbe has several products based on NGS, qPCR, and sanger technologies. The Innovation team is developing new technologies based on NGS and qPCR for next-stage products and services. The successful candidate will have the opportunity to join NuProbe, working under the guidance of the Innovation team lead to contribute to the new technology development.


PRIMARY RESPONSIBILITIES

  • (30%) Bioinformatics, NGS Data Analysis (Python, MATLAB preferred)
  • (70%) Leading projects and performing wet-lab experiments including, but not limited to NGS library preparation, sequencing, PCR, qPCR, and nucleic acid extraction

PRIMARY PURPOSE OF POSITION

The Scientist I executes most of the R&D protocol activity which is vital to the success of the company. This position handles sensitive data and comes with a high degree of trust.


Essential Job Duties and Responsibilities:

  • Experimental: Conceptualize and execute experiments, identifying resources needed.
  • Design and Analysis: Carry out design and perform data analysis using specific tools and software as needed, with ability to summarize the different variables included. Able to perform simple modifications on mature algorithm.
  • Data Interpretation: Identify the information content of an experiment, identify which questions the data answers and does not answer, making hypothesis identifying action items.
  • Leadership: Communicate with technicians and peers to ensure that experiments are executed as they were conceptualized.
  • Presentations: Carry out the effective presentation of the results collected for internal and external parties.
  • Independence: Able to carry out the functions above, spending no more than 10% of time necessary with peers and supervisor to carry out said functions.
  • Competencies:
    • Advanced understanding of multiple molecular biology techniques, which includes but is not limited to PCR and NGS
    • Basic to advanced understanding of at least two (2) of the following, ranked by importance:
      • Nucleic Acid kinetics and thermodynamic (e.g., hybridization thermodynamic)
      • Bioinformatics (e.g., reading and writing scripts to carry out data analysis using no-stock software)
      • Statistics
      • Molecular diagnostic/applied genetic (e.g., the clinical significance of mutations, the biology of mutations)
      • Knowledge of patent research
    • Basic understanding of at least two (2) of the following disciplines:
      • Logistics in paper writing
      • Logistics in patent writing
      • Manufacturing, production and FDA regulations
      • Cutting edge new technologies, depends on project requirements

Education/Experience Required

For external candidates:

  • PhD degree in molecular biology or related fields
  • At least two (2) years of relevant experience (PCR and NGS) in research
  • At least one (1) year peer review publication

Physical Demands:

This position requires sitting at a desk, standing, bending and extensive use of computer and other work-related electronic devices. Must be able to push, pull, hold files and confer in office spaces. During time of pandemic, this and other roles require the employee to wear a mask over the nose and mouth while on the work premises. Must be able to carry or pick-up items up to 25 pounds at any time. Some travel may be required to carry-out job responsibilities. Employees must keep safety rules and good work practices a priority. Any accommodations must be requested through Human Resources.


This job description describes the major responsibilities of the job. It does not include all aspects of the position, such as the potential additional duties assigned by management, and the requirement for flexibility in assisting others for the company's overall benefit.


NuProbe USA is an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.


BENEFITS

  • Contribute to the success of a growing reality
  • Competitive salary based on experience + benefits
  • Promotion in 1-2 years for successful candidates
  • Targeted year-end performance-based bonus
  • ESOP Stock Options
  • Company benefits (medical, dental, unlimited PTO, 401k, etc.)
  • Professional growth: At NuProbe, we believe in people, and we foster professional growth

VISA SPONSORSHIP:

NuProbe is willing to sponsor an H1-b work visa for the successful candidate.


About NuProbe USA:

NuProbe is a genomics company with proprietary technology to reduce the cost and improve the sensitivity of NGS by 100-fold. NuProbe's technologies have been featured in journals such as Nature Biomedical Engineering, Nature Chemistry, Cancer Discovery, and Nature Communications, in collaboration with collaborators from MD Anderson, Baylor College of Medicine, Thermo Fisher, Oxford Nanopore, and Microsoft Research. To date, NuProbe has raised more than $60M, and its US office based in Houston, TX has over 50 full-time employees. NuProbe's senior management team includes industry veterans from Adaptive Biotechnologies, Thermo Fisher, Nanostring, Roche, and Allergan.

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