Job description
Arcaea is a biology-first beauty company building a new ingredient toolset for the beauty and personal care industry. We are creating pioneering ingredients, products, and stories accessible uniquely through biology.
Arcaea is seeking an experienced Sr. Computational Biologist to join our team and play a critical role in developing our ingredient toolset for the beauty and personal care industry. As a member of the Arcaea team, you will be responsible for architecting Arcaea's computational strategic vision and road map, collaborating with internal and external parties to execute on the strategic vision, and providing technical expertise toward the design and execution of Arcaea's projects. This is a hybrid role that will require the candidate to travel to the Boston, MA headquarters 2-3 times a week.
WHAT YOU WILL DO:
- Architect Arcaea's computational strategic vision and road map
- Collaborate with internal and external parties to execute on the strategic vision
- Provide technical expertise toward the design and execution of Arcaea's projects
- Summarize and display complex data into actionable metrics to inform experimental design/next steps
- Create and troubleshoot (custom) software in order to enable high throughput analysis pipelines
- Analyze varied genomic data sets (transcriptomics, resequencing, genome assembly, genome annotation, metagenomics, epigenetics, etc.)
- Develop tools for manipulation and investigation of NGS datasets
- Perform comparative and phylogenetic review of genome and metagenome sequence data
- Run software and scripts while keeping excellent records
- Analyze large metagenomic datasets (microbiome data sets)
- Design, execute, review, and interpret experiments to provide recommendations towards product development strategies (in vitro and human studies)
- Oversee and/or develop molecular dynamics models
- Conduct a range of analysis including protein and peptide design and protein-ligand docking experiments
- Stay current on scientific literature (new methods, data analysis tools, etc) and cutting edge technology
- Communicate technical information to internal teams and/or external parties in the form of oral and written correspondence, presentations, and reports
- Develop technical insights based on research and scientific literature
- Work with cross-functional teams to implement new technologies into new product development pipelines
- Work effectively and efficiently on a tight deadline without drama or ego
WHAT WE SEEK:
- MS/PhD in life sciences, bioinformatics, computational biology, physical sciences, or equivalent experience
- 4+ years of experience in computational biology and/or data analysis, including at least 2 years of hands-on work experience with real data (either in an academic or industry environment)
- Demonstrated strong skills in computational biology
- Proven technical skills in problem solving, analytical techniques, data gathering, analysis, statistics, interpretation, and proficiency in method troubleshooting
- Loves to write elegant code (please provide a link to any publicly available code when applying)
- Experience with many or all of the following: Python, bash/unix scripting, samtools, bwa, snakemake, airflow, CWL, relational databases (SQL), GraphQL, distributed computing (AWS/Google Cloud), Docker, software version control (git)
- Highly independent with the ability to work with cross functional teams in a fast-paced environment
- Delivering on projects, on time
- Effective communicator, can explain complex science in layman terms
- Strong interpersonal skills
NICE TO HAVE (NOT REQUIRED):
- Experience with manipulation and visualization of genome, metagenome, and/or NGS datasets
- Experience with data mining
- Experience with analyzing microbiome data sets
- High level experience with DNA and RNA sequencing
- Experience with NGS data from Illumina and MinIon sequencing machines, (de novo) genome and hybrid assembly, and genome annotations
- Experience in research on host-microbiome interactions
- Knowledge of human skin biology and immunology
- Experience with systems biology and metabolic modeling
- Experience with molecular dynamics modeling
- Experience with protein-ligand docking
- Experience with protein modeling and design
- Familiar with Smartsheet, Jira, and Confluence
- Project management experience
- Passionate about keeping up with technology and new developments
We feel that it's important to point out the obvious here – there's a serious lack of diversity in both the scientific fields and beauty industry, and that needs to change. Our goal is to help drive that change. We are deeply committed to diversity, equality, and inclusion in all its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.
No candidate will meet every single desired qualification. If your experience looks a little different from what we've identified and you think you can bring value to the role, we'd love to learn more about you!
We're working with the powerful biological engineering platform at Ginkgo Bioworks, so we must remain mindful of the many ways our technology can – and will – impact people around the world. Ginkgo and Arcaea care about how this platform and the products created are used. Having a diverse team to build it gives us the best chance that it's something we'll be proud of as it continues to grow. Therefore, it's critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology in every industry.
We are committed to diversity, equality, and inclusion in all its practices. It is the policy of Arcaea to provide equal employment opportunities to all employees and employment applicants.
Agency and Third Party Recruiter Notice: Agencies that submit a resume to Arcaea must have a current executed Arcaea Agency Agreement executed by the Director, People Operations. In addition Agencies may only submit candidates to positions for which they have been invited to do so by an Arcaea Recruiter. All resumes must be sent to the Arcaea Recruiter under these terms or they will not be considered.
If you have a disability under the Americans with Disabilities Act or similar law, or you require religious accommodation, and you wish to discuss potential accommodations related to applying for employment at our company, please contact recruiting@arcaea.com.
Arcaea participates in E-verify to determine employment eligibility.
Disclaimer: This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee.
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