Job Description:

The Precision Medicine Department at Abbvie is committed to advancing drug development and patient care through building a deeper understanding of disease biology and developing tools to optimize clinical decision making and customize treatment for patients. Abbvie is seeking a highly motivated and experienced translational scientist to lead the development, planning, and execution of the clinical translational research and precision medicine strategy in inflammatory bowel.

Key Responsibilities:

• Define and implement the translational research and precision medicine strategy in inflammatory bowel disease. Responsibilities may extend from Lead Optimization in Discovery through mature product life cycle in Development and back translational activities:
  • Define translational research strategy in inflammatory bowel disease to support clinical success of pipeline assets, including PD/TE biomarkers, POM biomarkers, patient selection/stratification strategies, and development of novel disease biomarkers.
  • Manage the design, conduct, interpretation and reporting of biomarker data/activities for pipeline assets in line with the development, regulatory and commercial strategies
  • Lead asset-specific translational projects/teams in a matrix environment.
  • Coordinates appropriate scientific and medical activities with internal stakeholders (i.e. commercial, clinical operations, discovery, statistics, regulatory, etc.) to execute high quality biomarker strategies in the clinic.
  • Ensure, in collaboration with project leaders and asset-specific translational team members, that clinical translational sciences budgets, timelines, publication strategies and regulatory compliance requirements are factored into programs' scientific activities.
• Provide subject matter expertise on cross-functional teams defining broader corporate strategy in inflammatory bowel disease.
• Initiate new areas of investigation and implement cutting-edge technologies that are scientifically meaningful, reliable and can be incorporated directly into a clinical development program.
• Build and lead an internal team of highly experienced and accomplished translational scientists and develop productive collaborations with cross-functional teams.
• Establish external network and build collaborations that complement internal efforts to advance mechanistic understanding of therapeutics and inform development opportunities.
• Prepare and present summaries of translational data for discussions with key stake holders across multiple functional areas.

Qualifications:

• PhD and typically 10+ years of experience, Master’s Degree or equivalent education and typically 16+ years of experience, Bachelor’s Degree or equivalent education and typically 18+ years of experience in academia or industry.
• Strong scientific background in immunology or related field supported by publication record in these areas.
• Expertise in inflammatory bowel disease is highly desirable.
• Knowledge of clinical trial methodology, regulatory requirements governing clinical trials, companion diagnostics/in vitro diagnostics, protocol design, and/or experience in development strategy preferred.
• Demonstrated leadership in translational sciences (employing pharmacodynamic, predictive and exploratory biomarkers) and experience with development of assays including ligand binding assays, IHC/IF, gene expression profiling, flow cytometry.
• Ability to manage clinical translational programs and teams with moderate supervision.
• Demonstrate creative ‘out of the box’ thinking to solve difficult problems.
• Organization, detail oriented, and effective time management with an ability to adapt to changing priorities.
• Familiarity with data management and visualization tools and collaborating with computational biology to analyze complex data sets emerging from clinical trials.
• Excellent written and oral communication skills, ability to present the results in clear and concise manner.
• Strong interpersonal, influencing and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts.
• Experience managing junior scientists (PhD/MS) is a plus.

Key Leadership Competencies:

• Builds strong relationships with peers and cross functionally with partners to enable high performance.
• Learns fast, grasps difficult concepts, and can change course quickly where indicated.
• Strong communication and teamwork skills are essential as the candidate is expected to interact with diverse groups within Abbvie and through external collaborations.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, is open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
• Strong interpersonal and communication skills with demonstrated ability to work within a team environment.
  

Additional Information:

• Travel: 10%
• Job Type: Experienced
• Schedule: Full-time

AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.