Senior Bioprocess Engineer

Full Time
Boston, MA
Posted
Job description

SENIOR BIOPROCESS ENGINEER

Arcaea is building a new ingredient toolset for the beauty and personal care industry - one rooted in biotechnology with the aim of delivering radical performance and unparalleled sustainability that will also present new opportunities for storytelling. This role will be critical to shaping and driving Arcaea’s ethos around a “biology-first” future for the industry. Our mission is to create the most consequential personal care ingredients and brands of this century.

We are building an organization where technology and storytelling coexist in a symbiotic relationship. To accomplish our vision we will need to be really good at two things: consumer engagement and technical innovation - and they will need to work together in concert.

You will work closely with the Head of Biotechnology and supply chain where your main focus will be on scaling our precision fermentation processes and support downstream processing for a wide category of ingredients. You will be a key member in ensuring smooth scale-up to manufacturing of our novel biotech ingredients.


RESPONSIBILITIES

  • Develop a strategic plan and road map for scale-up & bio-manufacturing
  • Assess the strengths and weaknesses of processes and molecules
  • Support the design of scalable fermentation experiments, optimizing for titer and productivity of various microbial strains, including media development and metabolite characterization in collaboration with the analytical team.
  • Generate detailed SOPs and batch records for fermentation operations
  • Identification and onboarding of new CDMOs & CMOs
  • Responsible for technology transfers to CDMOs & CMOs
  • Management of external process development and manufacturing
  • Review of batch documentation along with associated analytical data
  • Represent the biomanufacturing function at cross functional meetings
  • Prepare technical reports, protocols and scientific presentations.
  • Responsibility for preparation of relevant regulatory documents
  • Deliver against agreed objectives and key results (OKRs)
  • Help build Arcaea’s culture
  • Work closely with internal stakeholders, and keep them informed of new developments & needs
  • Tracks emerging technologies and innovations in biomanufacturing as well as competitive activity and reports back to key stakeholders
  • Works closely with Head of Biotech, deployment, supply chain, and finance to develop cost, price, and margin scenarios
  • Maintain and share professional knowledge through education, networking, and presentations

QUALIFICATIONS / SKILLS:

Required Experience and Capabilities:

  • PhD with 2-3+ years of related experience, MS with 5-7+ years of related experience, or BS with 7+ years of related experience. 5+ years of experience must be in bio-manufacturing.
  • Track record of building and developing fermentation strategies
  • You have an in-depth understanding of fermentation optimization for scale-up development.
  • Detailed knowledge of the physiology and growth of at least one microorganism in an industrial context, specifically with respect to optimizing for robustness, titer, and productivity.
  • Demonstrated excellence in planning, executing, and analyzing experiments
  • Critical thinking and independence, ability to troubleshoot, solve difficult problems, and develop process improvements
  • Hands-on, motivated self-starter with a strong sense of initiative and attention to detail.
  • Excellent organizational skills and ability to manage multiple projects and excellent record-keeping
  • Strong communication and interpersonal skills
  • Flexible team player excited to collaborate with internal and external partners

Desired Experience and Capabilities:

  • Deep knowledge of the fermentation and DSP sectors
  • Proven record negotiating and closing contract clients
  • Project management experience
  • Start-up experience

We feel that it’s important to point out the obvious here – there’s a serious lack of diversity in both the scientific fields and beauty industry, and that needs to change. Our goal is to help drive that change. We are deeply committed to diversity, equality, and inclusion in all its practices, especially when it comes to growing our team. Our culture promotes inclusion and embraces how rewarding it is to work with people from all walks of life.

We’re working with the powerful biological engineering platform at Ginkgo Bioworks, so we must remain mindful of the many ways our technology can – and will – impact people around the world. Ginkgo and Arcaea care about how this platform and the products created are used. Having a diverse team to build it gives us the best chance that it’s something we’ll be proud of as it continues to grow. Therefore, it’s critical that we incorporate the diverse voices and visions of all those who play a role in the future of biology in every industry.

It is the policy of Arcaea to provide equal employment opportunities to all employees and employment applicants.


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